Trabec 1mg Used to treat Cancer Medicine, get price of Trabec 1mg Injection composition of Trabectedin 1mg Injection by Natco pharma ltd, #MedsDelta is Worldwide Suppliers, Traders , Dealer Of generic Yondelis etc
Trabec (Trabectedin) interacts with the minor groove of DNA and alkylates guanine at the N2 position, which bends towards the major groove. In this manner, it is thought that the drug affects various transcription factors involved in cell proliferation, particularly via the transcription-coupled nucleotide excision repair system. Trabec (Trabectedin) blocks the cell cycle at the G2 phase, while cells at the G1 phase are most sensitive to the drug. It also inhibits overexpression of the multidrug resistance-1 gene (MDR-1) coding for the P-glycoprotein that is a major factor responsible for cells developing resistance to cancer drugs.
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